The safety profile of neuraxial magnesium has not been properly addressed

The Missing Memristor has Not been Found

In 1971, not only the theoretical and by definition already existing 'ideal memristor' concept was introduced, but a real memristor device was suggested on grounds of the already known real inductors. The latter is a scientifically significant hypothesis grounded in fundamental symmetries of basic physics, here electro-magnetism. 2008 claimed the discovery of the "missing memristor." Controvers...

Has your kitchen been safety checked?

Has Culling Been Properly Assessed as a Valid and Justified Control Intervention Measure for Zoonotic Diseases?

In their PLoS Neglected Tropical Diseases research article ‘‘A Pilot Study for Control of Hyperendemic Cystic Hydatid Disease in China,’’ Zhang et al. [1] describe a research project conducted from 1987 to 1994 in Xinjiang, a multiethnic and multireligious province in western China. The study aimed to assess the efficacy and cost-effectiveness of applying monthly praziquantel treatment to dogs ...

Neuroauditory Toxicity of Artemisinin Combination Therapies—Have Safety Concerns Been Addressed?

Although artemisinin-based combination therapies (ACTs) are widely viewed as safe drugs with a wide therapeutic dose range, concerns about neuroauditory safety of artemisinins arose during their development. A decade ago, reviews of human data suggested a potential neuro-ototoxic effect, but the validity of these findings was questioned. With 5-10 years of programmatic use, emerging artemisinin...

Why has Not There been More Research of Concern?

Amid the renewed concern in the last several years about the potential for life science research to facilitate the spread of disease, a central plank of the policy response has been to enact processes for assessing the risks and benefits of "research of concern." The recent controversy regarding a proposed redaction of work on the modification of a H5N1 avian influenza virus is perhaps the most...